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SYNTHETIC NANOSTRUCTURES INCLUDING NUCLEIC ACIDS A

来源:微智科技网
专利内容由知识产权出版社提供

专利名称:SYNTHETIC NANOSTRUCTURES INCLUDING

NUCLEIC ACIDS AND/OR OTHER ENTITIES

发明人:C. Shad Thaxton,Chad A. Mirkin,Kaylin M.

McMahon,Sushant Tripathy,Raja KannanMutharasan,David M. Leander,Andrea Luthi

申请号:US14215569申请日:20140317

公开号:US20140294927A1公开日:20141002

摘要:Articles, compositions, kits, and methods relating to nanostructures, includingsynthetic nanostructures, are provided. Certain embodiments described herein includestructures having a core-shell type arrangement; for instance, a nanostructure core maybe surrounded by a shell including a material, such as a lipid bilayer, and may includeother components such as oligonucleotides. In some embodiments, the structures, whenintroduced into a subject, can be used to deliver nucleic acids and/or can regulate geneexpression. Accordingly, the structures described herein may be used to diagnose,prevent, treat or manage certain diseases or bodily conditions. In some cases, thestructures are both a therapeutic agent and a diagnostic agent.

申请人:C. Shad Thaxton,Chad A. Mirkin,Kaylin M. McMahon,Sushant Tripathy,RajaKannan Mutharasan,David M. Leander,Andrea Luthi

地址:Chicago IL US,Wilmette IL US,Chicago IL US,Evanston IL US,Chicago IL US,St. LouisMO US,Evanston IL US

国籍:US,US,US,US,US,US,US

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