专利内容由知识产权出版社提供
专利名称：PERSONALIZED PAIN MANAGEMENT AND
ANESTHESIA: PREEMPTIVE RISKIDENTIFICATION AND THERAPEUTICDECISION SUPPORT
发明人：SADHASIVAM,
Senthilkumar,CHIDAMBARAN,Vidya,MCAULIFFE, John,ZHANG,
Kejian,MELLER, Jarolsaw,PROWS, CynthiaA.,FUKUDA, Tsuyoshi
申请号：EP12854522.5申请日：20121129公开号：EP2785874B1公开日：20180926
摘要：Methods and compositions disclosed herein generally relate to methods ofimproving clinical and economic outcomes to address adverse effects related to
anesthesia, analgesics, opioids, and inadequate pain relief. Embodiments of the inventionrelate to the association between genes, specific polymorphisms of genes, and non-genetic factors with inadequate pain relief and anesthesia-, analgesic, and/or opioid-related adverse effects. Embodiments of the invention can be used to determine andmanage patient risk factors for development of adverse perioperative effects and canallow for personalized anesthesia and pain management for improvement of pain controland reduction of anesthesia-, analgesic-, and opioid-related adverse outcomes. Thesemethods and compositions apply to non-surgical pain management with opioids.
Therefore, patients who are genetically predisposed to risk of inadequate pain reliefand/or serious side effects from anesthesia, analgesics, and/or opioids can be identifiedand individualized treatment plans developed for implementation by the clinician toimprove clinical and economic outcomes.
申请人：CHILDRENS HOSPITAL MEDICAL CENTER
地址：US
国籍：US
代理机构：Haseltine Lake LLP
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