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12-Alpha-hydroxy steroids and their preparation

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专利名称:12-Alpha-hydroxy steroids and their

preparation

发明人:KIESLICH, KLAUS, DR.,KERB, ULRICH, DR.申请号:EP80102384.7申请日:19800502公开号:EP0019162B1公开日:19821201

摘要:1. Process for the manufacture of 12 alpha-hydroxysteroids of the generalformula I see diagramm : EP0019162,P3,F1 in which X represents a hydrogen atom or afluorine atom, R1 represents a hydrogen atom or a methyl group, and R2 represents ahydrogen atom or a hydroxy group, or R1 and R2 together represent an

isopropylidenedioxy group, characterised in that a steroid of the general formula II seediagramm : EP0019162,P3,F3 in which X, R1 and R2 have the meanings given above and R3represents a hydrogen atom or an alkanoyl group having from 1 to 6 carbon atoms, isfermented with a culture of Cercospora kaki (CBS 128 39).

申请人:SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN

地址:13342 Berlin DE

国籍:DE

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