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Aminoacyl and oligopeptidyl derivatives of allopur

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专利名称:Aminoacyl and oligopeptidyl derivatives of

allopurinol exhibiting immunostimulatoryactivity, and pharmaceutical formulationscontaining these substances

发明人:Marzi, Mauro,Minetti, Patrizia,Foresta,

Piero,Tinti, Maria Ornella

申请号:EP92830136.5申请日:19920320公开号:EP0506628A3公开日:19921021

摘要:The present invention concerns aminoacyl and oligopeptidyl derivatives ofallopurinol (1,5-dihydro-4H-pyrazolo-[3,4-d]-pyrimidin-4-one) of general formula (I), andrelated salts with pharmacologically-acceptable cations, in which n is an integer between2 and 6, preferably 5, Y is H or CO-A, in which A is a racemic or chiral amino acid, dipeptide,tripeptide, tetrapeptide, or pentapeptide chosen, respectively, from the goups consistingof:

申请人:Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.

地址:Viale Shakespeare, 47 I-00144 Roma IT

国籍:IT

代理机构:Cavattoni, Fabio

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