专利内容由知识产权出版社提供
专利名称：Novel Amino Alcohol Cationic Lipids for
Oligonucleotide Delivery
发明人：Brian W. Budzik,Steven L. Colletti,Darla
Danile Seifried,Mathew G. Stanton,Lu Tian
申请号：US13699451申请日：20110518
公开号：US20130150625A1公开日：20130613
摘要：The instant invention provides for novel cationic lipids that can be used incombination with other lipid components such as cholesterol and PEG-lipids to form lipidnanoparticles with oligonucleotides. It is an object of the instant invention to provide acationic lipid scaffold that is more efficacious than traditional cationic lipids. The presentinvention employs amino alcohols to enhance the efficiency of in vivo delivery of siRNA.
申请人：Brian W. Budzik,Steven L. Colletti,Darla Danile Seifried,Mathew G. Stanton,LuTian
地址：Perkiomenville PA US,Princeton Junction NJ US,Lansdale PA US,Marlton NJUS,Jamison PA US
国籍：US,US,US,US,US
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