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专利名称：Preparation and use of particulates
composed of adenovirus particles
发明人：Bruce L. Roberts,Charles Nicolette,Srinivas
Shankara
申请号：US09841836申请日：20010425
公开号：US200200012A1公开日：20020117
摘要：This invention provides particulates of adenoviral particles comprised ofindividual adenovirus virions complexed to an insoluble micro-platform material and forsuch compositions further comprised of a polynucleotide encoding an antigenic peptide.The invention further provides method for forming such complexes such that thecompositions are useful for transfecting phagocytic antigen presenting cells such asdendritic cells and for vaccinating a subject against disease.
申请人：ROBERTS BRUCE L.,NICOLETTE CHARLES,SHANKARA SRINIVAS
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