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COMPOSITION FOR PREVENTING, AMELIORATING, OR TREAT

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专利名称:COMPOSITION FOR PREVENTING,

AMELIORATING, OR TREATING

NEUROLOGICAL DISEASE CONTAININGOSMOTIN PEPTIDE AS ACTIVE INGREDIENT

发明人:Myeong Ok KIM申请号:US15553095申请日:20160303

公开号:US20180036365A1公开日:20180208

摘要:A method of preventing or treating neurological disease includes administeringto a subject in need thereof, a composition comprising an osmotin peptide selected fromthe group consisting of (a) an osmotin peptide having the amino acid sequence of SEQ IDNO: 1, and (b) an osmotin peptide having at least one amino acid residue substitution,deletion or insertion in the amino acid sequence of SEQ ID NO: 1. When a subject istreated with the osmotin peptide, nerve cells show no increase in growth rate, have littlecytotoxicity, and suppress cell death, and when the osmotin peptide is administered to ananimal model, the osmotin peptide infiltrated into the hippocampus of the brain and thehypothalamus of the brain, which is the deep part of the brain. Accordingly, the osmotinpeptide is used as a composition for preventing, ameliorating, or treating neurologicaldisease.

申请人:INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANGNATIONAL UNIVERSITY

地址:Gyeongsangnam-do KR

国籍:KR

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