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专利名称：Pharmaceutical formulation and process
comprising a solid dispersion of macrolide(tacrolimus)
发明人：Greg A. Brubaker,Thomas D. Mahon申请号：US12101500申请日：20080411公开号：US08222272B2公开日：20120717
摘要：The present invention relates to a pharmaceutical formulation and process forpreparing the same comprising an oral dosage formulation, such as a capsuleformulation, of a macrolide compound, such as tacrolimus, wherein the capsule
formulation contains both a solid dispersion of the macrolide along with a non-dispersedform of the macrolide. The pharmaceutical formulation according to the invention isbioequivalent to the FDA approved product according to a bioavailability studyconducted in humans.
申请人：Greg A. Brubaker,Thomas D. Mahon
地址：Sunbury OH US,West Jefferson OH US
国籍：US,US
代理机构：Pearne & Gordon LLP
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